antimicrobial activity of tetraacetylethylenediamine-sodium perborate versus sodium hypochlorite against enterococcus faecalis

background. this study evaluated the antimicrobial activity of tetraacetylethylenediamine-sodium perborate (taed-sp) in comparison to 2.5% and 5% sodium hypochlorite (naocl) against enterococcus faecalis. methods. a standard suspension of e. faecalis was inoculated on 60 plates containing mueller-hinton agar culture medium. four sterile disks of beckman filtration paper were placed on each plate. taed-sp, 5% and 2.5% naocl were placed on three disks. sterile physiologic saline was placed on the fourth disk as negative control. after 24-hour incubation, the diameter of the inhibition zone around the disks was measured using a transparent ruler. one-way analysis of variance (anova) was used to compare the mean zone of microbial growth in the groups. p-values less than 0.05 were considered statistically significant. results. there was a significant difference in the diameter of the inhibition zones between groups (p < 0.05). the tukey post hoc test showed a higher diameter of the inhibitory zone with taed-sp than that of 2.5% naocl. however, there were no significant differences between the inhibitory zones of taed-sp and 5% naocl. conclusion. taed-sp and 5% naocl have similar antibacterial activity against e. faecalis; however, taed-sp has a greater antibacterial effect compared to 2.5% naocl.